Thionyl Chloride → HCID 20095065, compound

HRID 1770155Notes

Reaction equation

HRID 1770155 reaction equation
S(Cl)([Cl:3])=O.[CH2:5]([CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([C:22]([OH:24])=O)[CH:19]=2)[CH2:14]1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]>>[CH2:5]([CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([C:22]([Cl:3])=[O:24])[CH:19]=2)[CH2:14]1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 20095034HCID 20095034, compound

Product 1

HCID 20095065HCID 20095065, compound

Procedure

4.8 g of thionyl chloride was added to 1.10 g (4.00 mM) of 2-octylindan-5-carboxylic acid, followed by refluxing for 1 hour. After the refluxing, an excessive thionyl chloride was distilled off under reduced pressure, followed by further distillation with benzene to obtain 2-octylindan-5-carbonyl chloride.

Workup

  1. temperatureby refluxing for 1 hour
  2. distillationAfter the refluxing, an excessive thionyl chloride was distilled off under reduced pressure
  3. distillationfollowed by further distillation with benzene

Sources & evidence

ORD record
ord-17f81db4d4e34723901dc25705592ec1
Source dataset
uspto-grants-1995_01
Patent number
US05385692

Reaction notes

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