Hydrazine hydrate (1:1) → HCID 20095051, compound

Participants

Reaction Steps

Subsequently, 1.01 g (3.11 mM) of 2-hexyl-5-(5-nitropyridine-2-yl)indan, 0.19 g of activated carbon and 0.02 g ferric chloride hexahydrate were mixed and stirred at room temperature. To the mixture, 0.96 ml of 80%-hydrazine hydrate (density: 1.03) was added dropwise, followed by stirring for 40 minutes at 70°-71.5° C. The resultant insoluble matter was removed by filtration and the filtrate was concentrated under reduced pressure, followed by addition of methanol and cooling in a refrigerator to obtain an insoluble matter. The insoluble matter was recovered by filtration to obtain 0.71 g of 2-hexyl-5-(5-aminopyridine-2-yl)indan (Yield: 77.5%).

Provenance & Evidence