Ethanol → HCID 20095063, compound

Participants

Reaction Steps

0.74 g (3.0 mM) of 2-hexylindan-5-boronic acid, 0.22 g (1.5 mM) of 3,6-dichloropyridazine, 2 ml of ethanol, 4 ml of benzene, 4 ml of 2M-sodium carbonate aqueous solution and 0.21 g of tetrakis (triphenylphosphine) palladium (O) were mixed and heat-refluxed for 2 hours under stirring. After the reaction, the reaction mixture was poured into ice water to precipitate a crystal. The crystal was recovered by filtration under reduced pressure and purified by silica gel column chromatography (eluent: toluene) and recrystallized from a mixture solvent (toluene/ethyl acetate) to obtain 0.57 g (1.19 mM) of 3,6-bis(2-hexylindan-5-yl)pyridazine (Yield: 79%). ##STR323##

Provenance & Evidence