HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → (4-formyl-2-methoxyphenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Vanillin | HCID 1183 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Solvent | Water | HCID 962 | — |
| Product | (4-formyl-2-methoxyphenoxy)acetic acid | HCID 686916 | 57% |
Reaction Steps
A solution of 30.4 g of 4-hydroxy-3-methoxybenzaldehyde, 31.2 g of chloroacetic acid and 34 g of potassium hydroxide in 300 ml of water was refluxed for 7 hours. After cooling, hydrochloric acid was added and the precipitate was filtered off and dried. Yield 57%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05385922 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-5c32c71f7c824a64a95b63dc21d954be |
| Source note | uspto-grants-1995_01 |