L-(+)-Cysteine → HCID 20095511, compound

Participants

Reaction Steps

A solution of 10 g of 3-phenylpropionaldehyde in THF was added to a solution of 10 g of cysteine in water. The resulting solution was stirred for 1 hour and then concentrated in vacuo. The precipitate was filtered off and washed with water and diethyl ether. The solid substance was dissolved in water which contained 12.5 g of potassium carbonate. 7.8 g of acetic anhydride were added at 0° C. and the resulting was stirred for 1 hour, after which the mixture was acidified to pH=2 with dilute sulphuric acid. This mixture was stirred for 30 minutes. The precipitate was filtered off, washed with water and dried. Yield 90%.

Provenance & Evidence