HCID 86747162, compound → HCID 86747161, compound

HRID 1770322Notes

Reaction equation

HRID 1770322 reaction equation
Cl.CN1C2=CCC(=O)C=C2[O:5][CH:4]1[CH2:13]CN.Cl.[CH3:17][N:18]1[C:22]2=[CH:23][CH2:24][C:25](=[O:27])[CH:26]=[C:21]2[S:20][CH:19]1[CH2:28][CH2:29][NH2:30]>>[CH3:17][N:18]1[C:22]2=[CH:23][CH2:24][C:25](=[O:27])[CH:26]=[C:21]2[S:20][CH:19]1[CH2:28][CH2:29][NH:30][C:4](=[O:5])[CH3:13]

Participants

3

Reactant 2

HCID 86747162HCID 86747162, compoundHCID 86747164HCID 86747164, compound

Product 1

HCID 86747161HCID 86747161, compoundYield 79%

Procedure

By replacing 2-(3-methyl-6-benzoxazolinonyl)ethylamine hydrochloride in Example 61 by 2-(3-methyl-6-benzothiazolinonyl)ethylamine hydrochloride, described in French Patent Application 90/11,866, the product of the title is obtained. Yield: 79% Melting point: 134°-136° C. Infrared spectrometry: 3280 cm-1, ν N--H (3080-2860) cm-1, ν C--H 1670 cm-1, ν CO(S--CO--N) 1630 cm-1, ν CO (amide) 1600 cm-1, ν C=C (aromatic) Nuclear Magnetic Resonance Spectrometry (CDCl3): 1.96 ppm, (s, 3H), COCH3 2.85 ppm, (t, 2H), CH2NHCOCH3 3.50 ppm, (unresolved peaks, 5H), CH2NHCOCH3 and NCH3 5.50 ppm, (signal, 1H), NH 6.95 ppm, (d, 1H), H4 7.20 ppm, (unresolved peaks, 2H), H5, H7

Workup

  1. customthe product of the title is obtained

Sources & evidence

ORD record
ord-0adb415861b142a9b79bd9dda0f0ab9e
Source dataset
uspto-grants-1995_01
Patent number
US05386034

Reaction notes

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