Methyl 4-(bromomethyl)benzoate → HCID 57944997, compound

HRID 1770474Notes

Reaction equation

HRID 1770474 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9]C)=[O:8])=[CH:5][CH:4]=1.[CH3:13][O:14][C:15]1[CH:35]=[CH:34][C:18]([CH2:19][NH:20][S:21]([C:24]2[CH:33]=[CH:32][C:27]([C:28]([O:30]C)=[O:29])=[CH:26][CH:25]=2)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[C:28]([C:27]1[CH:26]=[CH:25][C:24]([S:21]([N:20]([CH2:2][C:3]2[CH:12]=[CH:11][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=2)[CH2:19][C:18]2[CH:17]=[CH:16][C:15]([O:14][CH3:13])=[CH:35][CH:34]=2)(=[O:23])=[O:22])=[CH:33][CH:32]=1)([OH:30])=[O:29]

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 26527056Methyl 4-(N-(4-methoxybenzyl)sulfamoyl)benzoate

Product 1

HCID 57944997HCID 57944997, compound

Procedure

Prepared as in example 5-10 from methyl 4-(bromomethyl)benzoate and Methyl 4-(N-(4-methoxybenzyl)sulfamoyl)benzoate (example 5-10b). 1H NMR (400 MHz, DMSO-d6): δ, ppm: 3.65 (s, 3H), 4.24 (s, 2H), 4.33 (s, 2H), 6.71 (d, 2H, J=8 Hz), 6.95 (d, 2H, J=8 Hz), 7.14 (d, 2H, J=8 Hz). 7.73 (d, 2H, J=8 Hz), 7.89 (d, 2H, J=8 Hz), 8.06 (d, 2H, J=8 Hz).

Sources & evidence

ORD record
ord-aab2add285dd4847a8aa1ecd8a1b8f28
Source dataset
uspto-grants-2016_02
Patent number
US09247759B2

Reaction notes

Loading…