Glycine methyl ester → Methyl 2-(2-(methylthio)benzylamino)acetate

HRID 1770518Notes

Reaction equation

HRID 1770518 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH2:4][NH2:5].[CH3:7][S:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O>>[CH3:7][S:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH2:11][NH:5][CH2:4][C:3]([O:2][CH3:1])=[O:6]

Participants

3

Reactant 2

HCID 69221Glycine methyl esterHCID 2864432-(Methylthio)benzaldehyde

Product 1

HCID 57422438Methyl 2-(2-(methylthio)benzylamino)acetateYield 50%

Procedure

Prepared as in example 10-10a from glycine methyl ester and 2-(methylthio)benzaldehyde. Yield 50%. MS M+H calculated 226.1. Found 226.1

Sources & evidence

ORD record
ord-eb3a548d468049a9b4c8ee2a207a7eb4
Source dataset
uspto-grants-2016_02
Patent number
US09247759B2

Reaction notes

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