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HRID1770620

反应详情

EQUATION

反应方程式

HRID 1770620 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(CCl)n(C)n1
HCID4961270

5-(chloromethyl)-1,3-dimethyl-1H-pyrazole

C6H9ClN2

结构：Cc1noc(C)c1Cn1cc(N2C(=O)NC(C)(C)C2=O)cn1
HCID59524388

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)n(C)n1
HCID53373958

未命名化合物

PROCEDURE

实验过程

Prepared as in Example 12-16 from 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione (Example 12-16a) and 5-(chloromethyl)-1,3-dimethyl-1H-pyrazole. MS 412 (MH+). The title compound was shown to inhibit hT2R08 bitter receptor and had an 1050 of 0.23 μM.