HCID 67508230, compound → HCID 86665522, compound

Participants

Reaction Steps

Under a nitrogen atmosphere, palladium on carbon (10%, 280 mg) was added to a solution of 3-(((benzyloxy)carbonyl)amino)-N-(2-methoxyethyl)-N,N,3-trimethylbutan-1-aminium chloride (1.3 g, 3.5 mmol) in 12 mL of methanol. The flask was degassed and placed under a hydrogen atmosphere, stirring for 18 hours at room temperature. The suspension was filtered through a pad of Celite® washing with methanol, and the filtrate was concentrated under reduced pressure to give about 835 mg of a clear oil. 1H NMR (D2O, 400 MHz) δ 1.15 (s, 6H), 1.87-1.92 (m, 2H), 3.06 (s, 6H), 3.30 (s, 3H), 3.39-3.43 (m, 2H), 3.49-3.51 (m, 2H), 3.79-3.80 (m, 2H); LRMS (ESI/APCI) m/z 189 [M]+

Provenance & Evidence