Cesium carbonate → HCID 67509414, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 4-(mercaptomethyl)-4-methyloxazolidin-2-one (1.79 g, 12.2 mmol) in N,N-dimethylformamide (20 ml) was added cesium carbonate (520 mg, 1.60 mmol) and 2-vinyloxirane (2.34 g, 33.4 mmol). The solution was heated to 60° C. for 14 hours, cooled to room temperature, concentrated in vacuo, and purified by flash chromatography (30% to 100% ethyl acetate in hexanes) to afford the title compound as a clear oil (quantitative). LRMS (ESI/APCI) m/z 218 [M+H]+.

Provenance & Evidence