HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Carboxypentyl 5-amino-4-oxopentanoate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(benzyloxycarbonyl)pentyl 5-(Cbz-amino)-4-oxopentanoate | HCID 90034528 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 5-Carboxypentyl 5-amino-4-oxopentanoate hydrochloride | HCID 90034485 | 77% |
Reaction Steps
This compound was prepared from the product of 9b (0.45 g; 0.96 mmol), 12 M HCl (0.08 mL; 0.96 mmol), 10% Pd/C (100 mg), hydrogen gas, and 2-propanol (25 mL) using the procedure in Example 8d. 0.20 g (77%) product was obtained (white solid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249086B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-db51d748763448fbbc69141a23e4fc1c |
| Source note | uspto-grants-2016_02 |