反应详情

This compound was prepared from the product of 10a (0.79 g; 2.5 mmol) and 8b (1.0 g; 2.5 mmol) according to Procedure C. The reaction time was 2 days. The crude product was purified on a 80×45 mm silica gel 60 column eluted with ethyl acetate-hexane (1:1) (1000 mL) collecting 13×50 mL fractions. Fractions containing the product (3-6) were collected, and after evaporation 0.83 g (67%) product was obtained (amber oil that solidified to a waxy solid on standing in the freezer, mp 52-54° C.).

1. customThe crude product was purified on a 80×45 mm silica gel 60 column
2. washeluted with ethyl acetate-hexane (1:1) (1000 mL)
3. customcollecting 13×50 mL fractions
4. additionFractions containing the product (3-6)
5. customwere collected
6. customafter evaporation 0.83 g (67%) product
7. customwas obtained (amber oil that