反应详情

This compound was prepared from the product of 13a (0.96 g; 2.7 mmol) and 8b (1.0 g; 2.5 mmol) according to Procedure C. The crude product was purified on a 70×45 mm silica gel 60 column eluted with ethyl acetate-hexane (1:1) (1000 mL) collecting 13×50 mL fractions. The fraction containing the product (3) was evaporated and 0.69 g (47%) product was obtained (pinkish solid, mp 70-72° C.).

1. customThe crude product was purified on a 70×45 mm silica gel 60 column
2. washeluted with ethyl acetate-hexane (1:1) (1000 mL)
3. customcollecting 13×50 mL fractions
4. additionThe fraction containing the product (3)
5. customwas evaporated