Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | HCID 131734646 | HCID 131734646 | — |
| Product | HCID 88414954 | HCID 88414954 | 78% |
Reaction Steps
19.5 g 2-(3,4-dioxomethylenebenzyl)ethylthioamide (0.1 mol) was dissolved in 100 mL DMF, to which 12.6 g 1,3-dichloroacetone (0.1 mol) was added at room temperature. The reaction solution was heated at 60° C. for 3 hours, and then poured into ice water to isolate a solid. After sucking filtration and drying, 20.8 g off-white solid was obtained. Yield: 78%, MS: 268 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09249106B2 |
|---|
| Source dataset | uspto-grants-2016_02 |
|---|
| ORD ID | ord-d1179e5bbb7e47b48cb587a6fbe654db |
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| Source note | uspto-grants-2016_02 |
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