Benzoyl chloride → HCID 131734650, compound

HRID 1771134Notes

Reaction equation

HRID 1771134 reaction equation
[NH2:1][CH:2]([C:6]#[N:7])[C:3]([NH2:5])=[O:4].[C:8](Cl)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>N1C=CC=CC=1>[C:8]([NH:1][C@H:2]([C:3]([NH2:5])=[O:4])[C:6]#[N:7])(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 983412-Amino-2-cyanoacetamide

Product 1

HCID 131734650HCID 131734650, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

To a solution of 2-amino-2-cyanacetamide (8 g, 0.08 mol) in pyridine (10 mL) is added a solution of benzoyl chloride (0.08 mol) in pyridine (15 mL) and the mixture is stirred at rt for 40 min. It is then concentrated under reduced pressure to provide crude product which is used in the next step without further purification.

Workup

  1. concentrationIt is then concentrated under reduced pressure
  2. customto provide crude product which
  3. customis used in the next step without further purification

Sources & evidence

ORD record
ord-baa8a52391394dd19df2eaa57f76dbd0
Source dataset
uspto-grants-2016_02
Patent number
US09249114B2

Reaction notes

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