Methanol → 1'-Benzyl-6-bromo-4-hydroxy-spiro[chromane-2,4'-piperidine]
Reaction equation
[BH4-:25].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][cH:15][c:16]([Br:22])[cH:17][c:18]3[C:19](=[O:21])[CH2:20]2)[CH2:23][CH2:24]1.[CH3:28][OH:29].[Na+:26].[OH2:27]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([O:12][c:13]3[cH:14][cH:15][c:16]([Br:22])[cH:17][c:18]3[CH:19]([OH:21])[CH2:20]2)[CH2:23][CH2:24]1Participants
6
Sources & evidence
- ORD record
- ord-9204bf60d0f440f58d41a4d7c0a4419d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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