Hydrazine → HCID 90031922, compound

Participants

Reaction Steps

Synthesized according to General Procedure C: 51g (3.73 g, 12.7 mmol, 1.0 equiv.), anhydrous hydrazine (1.6 mL, 50.8 mmol, 4.0 equiv.), EtOH (25 mL, 0.5 M). 46g (2.28 g, 64.1%) was obtained as a white solid after extraction without further purification. 1H-NMR (500 MHz, CDCl3) δ 1H-NMR (500 MHz, CDCl3) δ 8.09 (br s, 1H), 7.37-7.33 (m, 2H), 7.06-7.02 (m, 2H), 3.85 (br s, 2H), 3.70 (br s, 2H), 3.42 (br s, 2H), 3.06 (s, 2H), 2.48 (br s, 4H). 13C-NMR (125 MHz, CDCl3) δ 169.8, 169.5, 163.5 (d, JC-F=249.1 Hz), 131.5 (d, JC-F=2.8 Hz), 129.4 (d, JC-F=9.1 Hz), 115.7 (d, JC-F=22.0 Hz), 60.6, 53.5 (br), 47.7 (br), 42.3 (br). 19F-NMR (470 MHz, CDCl3) δ −113.1. HRMS (ESI): 281.1409 (M+1); calcd. for C13H1sFN4O2: 281.1414.

Provenance & Evidence