N-bromobutanimide → HCID 86676116, compound

HRID 1771307Notes

Reaction equation

HRID 1771307 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[N:10]=[C:11]([NH2:15])[N:12]=[N:13][CH:14]=1.[Br:16]N1C(=O)CCC1=O>>[Br:16][C:14]1[N:13]=[N:12][C:11]([NH2:15])=[N:10][C:9]=1[C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[F:1]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 43134547HCID 43134547, compound

Product 1

HCID 86676116HCID 86676116, compoundYield 21.6%

Procedure

6-Bromo-5-(2,4-difluorophenyl)-1,2,4-triazin-3-amine (0.13 g, 21%) was prepared from 5-(2,4-difluorophenyl)-1,2,4-triazin-3-amine (0.45 g, 2.1 mmol) and N-bromosuccinimide (0.49 g, 2.80 mmol) according to the general procedure of Preparation 3.

Workup

  1. customaccording to the general procedure of Preparation 3

Sources & evidence

ORD record
ord-3921480f5ceb4cfd85f7e04bbf2eaa5d
Source dataset
uspto-grants-2016_02
Patent number
US09249130B2

Reaction notes

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