(1-Benzofuran-5-yl)boronic acid → HCID 67363806, compound

HRID 1771345Notes

Reaction equation

HRID 1771345 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[O:15]1[C:19]2[CH:20]=[CH:21][C:22](B(O)O)=[CH:23][C:18]=2[CH:17]=[CH:16]1>>[O:15]1[C:19]2[CH:20]=[CH:21][C:22]([C:2]3[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=3[C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)=[CH:23][C:18]=2[CH:17]=[CH:16]1

Participants

3

Reactant 2

HCID 4197999(1-Benzofuran-5-yl)boronic acidHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 67363806HCID 67363806, compoundYield 47%

Procedure

6-(1-benzofuran-5-yl)-5-phenyl-1,2,4-triazin-3-amine (225 mg, 47%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.50 g, 1.99 mmol) and benzofuran-5 boronic acid (0.32 g, 1.99 mmol) according to the general procedure of Example 1.

Sources & evidence

ORD record
ord-5966c93a76f1479ba473e41b99ff73ee
Source dataset
uspto-grants-2016_02
Patent number
US09249130B2

Reaction notes

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