3-Methylpiperidine → HCID 67363531, compound

HRID 1771353Notes

Reaction equation

HRID 1771353 reaction equation
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:15][CH:16]1[CH2:21][CH2:20][CH2:19][NH:18][CH2:17]1>>[CH3:15][CH:16]1[CH2:21][CH2:20][CH2:19][N:18]([C:2]2[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:17]1

Participants

3

Reactant 2

HCID 790813-MethylpiperidineHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

Product 1

HCID 67363531HCID 67363531, compoundYield 14%

Procedure

6-(3-Methylpiperidin-1-yl)-5-phenyl-1,2,4-triazin-3-amine (30 mg, 14%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.21 g, 0.80 mmol) and 3-methylpiperidine (0.21 g, 1.92 mmol) according to the general procedure of Example 2.

Sources & evidence

ORD record
ord-4db3f560f88c4f5d850a0b79e1e812a2
Source dataset
uspto-grants-2016_02
Patent number
US09249130B2

Reaction notes

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