HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71766904, compound → HCID 71766907, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71766904 | HCID 71766904 | — |
| Reactant | HCID 178514179 | HCID 178514179 | — |
| Catalyst | HCID 178418851 | HCID 178418851 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 71766907 | HCID 71766907 | — |
Reaction Conditions
| Temperature | 160 °C |
|---|
Reaction Steps
A mixture of 2-(5-chloroisochroman-1-yl)-4,5-dihydro-1H-imidazole (50 mg), dicyanozinc (25 mg), bis(tri-t-butylphosphine)palladium(0) (3 mg) and DMF (2 ml) was stirred in microwave reactor at 160° C. for 30 minutes. The title compound was purified with separation methods F and G. (Yield 22 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249127B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-cc1510cec0f14b289b154a84fc77cdcd |
| Source note | uspto-grants-2016_02 |