HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Thioglycolate → HCID 89851657, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | HCID 15364878 | HCID 15364878 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 89851657 | HCID 89851657 | 74.5% |
Reaction Steps
A mixture of methyl 2-mercaptoacetate (2.2 g), 2-bromophenethyl methanesulfonate (5.7 g), 2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepine (3.7 g) and THF (30 ml) was stirred at ambient temperature for 1.5 hrs and separation method A and E yielded the title compound (4.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249127B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-38b401e66003443585a35054ddcf4e4e |
| Source note | uspto-grants-2016_02 |