1,2-Ethanediamine, 4-methylbenzenesulfonate (1:?) → HCID 89851886, compound

Participants

Reaction Conditions

Reaction Steps

3-Methyl-1,3-dihydrobenzo[de]isochromene-1-carbonitrile (100 mg) was mixed with ethylene diamine mono-p-toluenesulfonic acid salt (111 mg) and the mixture was heated to 200° C. After 3 hours reaction was cooled to room temperature. Purification of the mixture by column chromatography with neutral alumina (ethyl acetate-heptane) afforded 11 mg of 2-(3-methyl-1,3-dihydrobenzo[de]isochromen-1-yl)-4,5-dihydro-1H-imidazole that was converted to the title compound using salt formation method A. (Yield 10 mg).

Provenance & Evidence