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HRID1771468

反应详情

EQUATION

反应方程式

HRID 1771468 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1
HCID11087024

Methyl 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

C15H21BO4

结构：Oc1ccc2cc(Br)ccc2c1F
HCID11241940

6-BROMO-1-FLUORONAPHTHALEN-2-OL

C10H6BrFO

2 次

PRODUCTS

生成物

1
结构：Cc1cc(C(=O)O)ccc1-c1ccc2c(F)c(O)ccc2c1
HCID57387165

未命名化合物

PROCEDURE

实验过程

Followed the coupling procedure described in Example 29 starting from 6-bromo-1-fluoronaphthalen-2-ol (Intermediate 13) and methyl 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate. 1H-NMR (DMSO-d6, 300 MHz, TMS): δ 12.90 (b, 1H), 10.17 (b, 1H), 7.84-7.97 (m, 4H), 7.70 (d, 1H), 7.54 (d, 1H), 7.41 (d, 1H), 7.30 (t, 1H), 2.33 (s, 3H). MS (ESI): m/z=295.25 [MA]−.