huagongshe.com
HRID1771563

反应详情

EQUATION

反应方程式

HRID 1771563 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2ccc(NC(=O)NCCF)cc2)OC1(C)C
HCID44607353

未命名化合物

2 次

结构：C[C@H]1COCCN1c1ccnc(Cl)n1
HCID72942067

未命名化合物

2 次

PRODUCTS

生成物

1
结构：C[C@H]1COCCN1c1ccnc(-c2ccc(NC(=O)NCCF)cc2)n1
HCID53379665

未命名化合物

PROCEDURE

实验过程

Method as described for example 49 using (S)-4-(2-chloropyrimidin-4-yl)-3-methylmorpholine (intermediate 3) and 1-(2-fluoroethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (intermediate 19). The mixture was purified by prep HPLC at high pH to afford the title compound. (15 mg, 9%).

WORKUP

后处理

  1. customThe mixture was purified by prep HPLC at high pH