2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → N-[6-[2-(methoxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide

HRID 177158Notes

Reaction equation

HRID 177158 reaction equation
[CH3:19][O:20][CH2:21][CH:22]1[N:23]([c:27]2[cH:28][cH:29][c:30]([NH2:33])[cH:31][n:32]2)[CH2:24][CH2:25][CH2:26]1.[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:13])[OH:14])[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[o:8][c:9]([C:15]([F:16])([F:17])[F:18])[c:10]([C:12](=[O:14])[NH:33][c:30]3[cH:29][cH:28][c:27]([N:23]4[CH:22]([CH2:21][O:20][CH3:19])[CH2:26][CH2:25][CH2:24]4)[n:32][cH:31]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 27764382-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 67535523HCID 67535523, compound

Product 1

HCID 178494505N-[6-[2-(methoxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide

Sources & evidence

ORD record
ord-d505bb0a5fbc4183afc95218eb66a860
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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