HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxycyclobutan-1-amine → HCID 67382557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxycyclobutan-1-amine | HCID 53302285 | — |
| Reactant | (S)-phenyl(4-(6-(5-fluoro-2-(methylsulfonyl)phenyl)-2-(3-methylmorpholino)pyrimidin-4-yl)phenyl)carbamate | HCID 89717157 | — |
| Product | HCID 67382557 | HCID 67382557 | — |
Reaction Steps
Method as described for example 58 using intermediate 32 (100 mg, 0.18 mmol) 3-methoxycyclobutanamine (22 mg, 0.213 mmol). The reaction mixture was purified by prep HPLC at low pH to afford the title compound. (37 mg, 30%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249129B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-32940fa81ff3447bafd7c9046a78d45e |
| Source note | uspto-grants-2016_02 |