HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloro-4-methoxy-2-nitrobenzene → 2,6-Dichloro-3-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloro-4-methoxy-2-nitrobenzene | HCID 20513886 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2,6-Dichloro-3-methoxyaniline | HCID 20513888 | 104.1% |
Reaction Steps
To a solution of 1,3-dichloro-4-methoxy-2-nitro-benzene (550 mg, 2.5 mmol, 1.0 eq) in EtOAc (20 mL) was added Pd/C (10% Pd, 50 mg) and the reaction was stirred under a hydrogen atmosphere overnight. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give the title compound (500 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249085B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-54c145e838a04a48bf8ebd85dace5a0b |
| Source note | uspto-grants-2016_02 |