HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydrazinylpyridine hydrochloride → HCID 89602527, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydrazinylpyridine hydrochloride | HCID 23143454 | — |
| Reactant | 1-(3-chloro-4-fluorophenyl)-5-(3-fluoro-5-trifluoromethoxyphenyl)-1H-pyrazole-3-carboxylic acid | HCID 58277289 | — |
| Reactant | Lithium 1-(3-bromo-5-trifluoromethoxy phenyl)-4-ethoxy-3,4-dioxobut-1-en-1-olate | HCID 131734661 | — |
| Product | HCID 89602527 | HCID 89602527 | — |
Reaction Steps
1.10 g (2.40 mmol) of the compound from example 3A is reacted with 525 mg (3.61 mmol) 3-pyridylhydrazine hydrochloride in a manner analogous to the synthesis of the compound from example 8A. Following hydrolysis, 557 mg (54% of theoretical yield) of the title compound is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249148B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-955c215cccd746a6b5d77c3dc6579681 |
| Source note | uspto-grants-2016_02 |