HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1772025Generated: October 26, 2026
1,7-Naphthyridin-8-amine → HCID 86667814, compound
https://huagongshe.com/reaction/1772025
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,7-Naphthyridin-8-amine | HCID 2737037 | — |
| Reactant | O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine | HCID 11830845 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86667814 | HCID 86667814 | 80.8% |
Reaction Steps
To a solution of 1,7-naphthyridin-8-amine (600 mg, 4.13 mmol) in DCM (5 mL) was added a solution of O-(mesitylsulfonyl)hydroxylamine (2.7 g, 12.4 mmol) in DCM (10 mL) at 0° C. The mixture was stirred at 0° C. for 2 h. The precipitate was filtered and collected to give 8-imino-1,7-naphthyridin-7(8H)-amine-2,4,6-trimethylbenzenesulfonate as a brown solid (1.2 g, yield 67%). ESI MS: m/z 161.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09249162B2 |
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| Source dataset | uspto-grants-2016_02 |
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| ORD ID | ord-1d46f4df65e6431c9f0ff6094791ee48 |
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| Source note | uspto-grants-2016_02 |
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