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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1772060Generated: November 4, 2026

Dimethylformamide → HCID 86667820, compound

https://huagongshe.com/reaction/1772060

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantOxalyl chlorideHCID 65578—
ReactantHCID 68089388HCID 68089388—
SolventDichloromethaneHCID 6344—
ProductHCID 86667820HCID 8666782096%

Reaction Steps

To a solution of 3-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)butanoic acid (200 mg, 0.086 mmol) in DCM (15 mL) was added oxalyl chloride (3 mL) and DMF (0.1 mL). The mixture was stirred at room temperature for 2 h. The mixture was then evaporated under reduced pressure to give the product as a brown solid (208 mg, 96% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249162B2
Source datasetuspto-grants-2016_02
ORD IDord-f5378ab99342422bacf28317783f96c5
Source noteuspto-grants-2016_02