HCID 11211940, compound → HCID 66781123, compound

HRID 1772303Notes

Reaction equation

HRID 1772303 reaction equation
[Na:1].N1C(N)=C2C(N(C([C@@H]([C@H](CO)OCP(O)(O)=O)O)=O)C=N2)=NC=1.[N:25]1([C:33]([C@@H:35]([C@H:37]([CH2:50][OH:51])[O:38][CH2:39][P:40]([O:46]C(C)C)([O:42]C(C)C)=[O:41])[OH:36])=[O:34])[CH:32]=[CH:31][C:29]([NH2:30])=[N:28][C:26]1=[O:27]>>[Na:1].[N:25]1([C:33]([C@@H:35]([C@H:37]([CH2:50][OH:51])[O:38][CH2:39][P:40]([OH:42])([OH:46])=[O:41])[OH:36])=[O:34])[CH:32]=[CH:31][C:29]([NH2:30])=[N:28][C:26]1=[O:27]

Participants

3

Reactant 2

HCID 11211940HCID 11211940, compoundHCID 66781133HCID 66781133, compound

Product 1

HCID 66781123HCID 66781123, compoundYield 43%

Procedure

This compound was prepared as described for 3a, using 18 (150 mg, 0.38 mmol) as a starting material. Compound 3d (58 mg, 0.16 mmol) was obtained as a colorless solid, in 43% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-e0d1ab99e5f74d09895d1875f7a75b14
Source dataset
uspto-grants-2016_02
Patent number
US09249177B2

Reaction notes

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