HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4'-chlorobenzophenone → 5-(4-Chlorophenyl)spiro[benzo[e][1,4]diazepine-3,1'-cyclopropan]-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4'-chlorobenzophenone | HCID 76166 | — |
| Reactant | (2-Amino-4,5-dimethylthiophen-3-yl)(4-chlorophenyl)methanone | HCID 719710 | — |
| Reactant | 4-(4-chlorophenyl)-2,3,6,6,9-pentamethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine | HCID 54588764 | — |
| Product | 5-(4-Chlorophenyl)spiro[benzo[e][1,4]diazepine-3,1'-cyclopropan]-2(1H)-one | HCID 67818282 | — |
Reaction Steps
A procedure analogous to that set forth in the synthesis of Compound 214 was followed, with the exception that (2-aminophenyl)(4-chlorophenyl)methanone was used as starting material instead of (2-amino-4,5-dimethylthiophen-3-yl)(4-chlorophenyl)methanone. LRMS (M+H)+: 297 m/z.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249161B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-64ea2142a7d641c2ba2e1a51e1b7c2b7 |
| Source note | uspto-grants-2016_02 |