反应详情

A procedure analogous to that set forth for Compound 202 was followed, with the exception that 5-(4-chlorophenyl)spiro[benzo[e][1,4]diazepine-3,1′-cyclopropan]-2(1H)-one was used as starting material. LRMS (M+H)+: 335 m/z. 1H NMR (400 MHz, DMSO-d6) δ 7.74-7.79 (m, 2H), 7.46-7.58 (m, 5H), 7.32 (d, J=7.55 Hz, 1H), 2.58 (s, 3H), 1.67-1.77 (m, 1H), 1.34-1.44 (m, 1H), 0.67-0.83 (m, 2H).