反应详情

A procedure analogous to the scheme set forth for the synthesis of Compound 215 was followed, with the exception that (R)-propane-1,2-diol was used as starting material. LRMS (M+H)+: 383 m/z. 1H NMR (400 MHz, DMSO-d6) δ 7.50 (s, 4H), 3.80 (t, J=6.98 Hz, 1H), 2.55-2.63 (m, 3H), 2.39 (s, 3H), 1.95-2.03 (m, 1H), 1.58 (s, 3H), 1.39 (d, J=5.95 Hz, 1H), 1.05-1.12 (m, 1H), 0.79 (d, J=5.49 Hz, 3H).