Dimethyl Sulfoxide → 6-{[(2-Amino-1,3-thiazol-4-yl)methyl]amino}-5-fluoro-4-hydrazino-2-methylpyrimidine

HRID 177254Notes

Reaction equation

HRID 177254 reaction equation
[CH3:21][S:22]([CH3:23])=[O:24].[NH2:19][NH2:20].[NH2:1][c:2]1[s:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]([CH3:17])[n:12][c:13]([Cl:16])[c:14]2[F:15])[n:6]1.[OH2:18]>>[NH2:1][c:2]1[s:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]([CH3:17])[n:12][c:13]([NH:19][NH2:20])[c:14]2[F:15])[n:6]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 9321HydrazineHCID 86636959N-[(2-amino-1,3-thiazol-4-yl)methyl]-6-chloro-5-fluoro-2-methyl-4-pyrimidinamine

Product 1

HCID 866369606-{[(2-Amino-1,3-thiazol-4-yl)methyl]amino}-5-fluoro-4-hydrazino-2-methylpyrimidine

Sources & evidence

ORD record
ord-93f7a622682e4306a72e8eab4d8f4c5c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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