2-Cyanopyridine-5-boronic acid pinacol ester → (E)-5-(8-Morpholino-2-(2-(quinolin-2-yl)vinyl)imidazo[1,2-a]pyrazin-5-yl)picolinonitrile

Participants

Reaction Steps

Compound 2b (800 mg, 1.84 mmol) was subjected to Suzuki coupling conditions with compound 1f using the reaction conditions described in Example 1, Step G to obtain compound 2c as a yellow solid (500 mg, 59% yield). Mass Spectrum (LCMS, ESI pos.): Calcd. for C27H21N7O: 460.2 (M+H). found: 460.3.

Provenance & Evidence