Sodium Azide → HCID 178419988, compound

Participants

Reaction Steps

Compound 3b (300 mg, 0.650 mmol) was treated with NaN3 as described in Example 1, Step H to obtain the title compound 77 as a light yellow solid (37.2 mg, 10% yield). 1H-NMR (300 MHz, DMSO-d6) δ (ppm): 8.79 (s, 1H), 8.26 (d, J=8.4 Hz, 1H), 8.15 (d, J=8.1 Hz, 1H), 8.04-8.02 (m, 1H), 7.92 (d, J=8.4 Hz, 2H), 7.80 (s, 1H), 7.70 (t, J=7.2 Hz, 1H), 7.56-7.46 (m, 3H), 4.21-4.09 (m, 4H), 3.75-3.65 (m, 4H), 3.35-3.25 (m, 4H). Mass Spectrum (LCMS, ESI pos.): Calcd. for C27H24N10O: 505.2 (M+H). Found 505.3.

Provenance & Evidence