HRID1772613
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Compound 3a (400 mg, 0.910 mmol) was subjected to Suzuki coupling conditions with 1-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2-[[2-(trimethylsilyl)ethoxy]methyl]-2,3-dihydro-1H-1,2,4-triazol-3-one (1.14 g, 2.73 mmol) using the reaction conditions described in Example 1, Step G to obtain compound 11e as a brown solid (148 mg, 25% yield). Mass Spectrum (LCMS, ESI pos.): Calcd. for C35H40N8O3Si: 649.3 (M+H). Found 649.3.
WORKUP
后处理
- customthe reaction conditions