HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroquinoline → HCID 117728336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroquinoline | HCID 11928 | — |
| Reactant | (5-Bromo-8-morpholinoimidazo[1,2-a]pyrazin-2-yl)methanol | HCID 117727888 | — |
| Product | HCID 117728336 | HCID 117728336 | 75% |
Reaction Steps
Compound 1e (10.0 g, 30.4 mmol) was treated with 2-chloroquinoline using the reaction conditions described in Example 1, Step I to obtain compound 15a as a white solid (10.4 g, 75% yield). Mass Spectrum (LCMS, ESI pos.): Calcd. for C20H18BrN5O2: 440.1 (M+H). found: 440.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249163B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-c4b96c18bda6461fb4f864c2255b1915 |
| Source note | uspto-grants-2016_02 |