HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate → tert-Butyl 4-(5-(2-(hydroxymethyl)-8-morpholinoimidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate | HCID 16217947 | — |
| Reactant | (8-Morpholinoimidazo[1,2-a]pyrazin-2-yl)methanol | HCID 117728187 | — |
| Product | tert-Butyl 4-(5-(2-(hydroxymethyl)-8-morpholinoimidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)piperazine-1-carboxylate | HCID 117733761 | — |
Reaction Steps
Compound 1d was subjected to Suzuki coupling reaction conditions with tert-butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate using the method described in Example 1, Step G to obtain compound 30a. Mass Spectrum (LCMS, ESI pos.) Calcd. for C25H33N7O4: 496.2 (M+H). Found 496.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249163B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-22e8970bcaf44415bfc376cf5ae7ec34 |
| Source note | uspto-grants-2016_02 |