HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl Formate → tert-Butyl (5-(8-morpholino-2-((quinolin-2-yloxy)methyl)imidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl Formate | HCID 61207 | — |
| Reactant | tert-butyl N-(5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate | HCID 17750222 | — |
| Reactant | HCID 117728336 | HCID 117728336 | — |
| Product | tert-Butyl (5-(8-morpholino-2-((quinolin-2-yloxy)methyl)imidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)carbamate | HCID 117732286 | — |
Reaction Steps
Compound 48a was prepared from compound 15a and 2-(BOC-amino)pyridine-5-boronic acid pinacol ester according to procedure described in Example 13, Step A. Mass Spectrum (LCMS, ESI pos.) Calcd. For C30H31N7O4: 453.3 (M+H-BOC). Found 554.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249163B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-4f272c3f6a514db689587a1590536473 |
| Source note | uspto-grants-2016_02 |