2-Chloropyridine-5-boronic acid → HCID 117728148, compound

HRID 1772692Notes

Reaction equation

HRID 1772692 reaction equation
Br[C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][O:12][C:13]3[CH:22]=[CH:21][C:20]4[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=4)[N:14]=3)[N:10]=[C:6]2[C:5]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[N:4][CH:3]=1.[Cl:29][C:30]1[CH:35]=[CH:34][C:33](B(O)O)=[CH:32][N:31]=1>>[Cl:29][C:30]1[N:31]=[CH:32][C:33]([C:2]2[N:7]3[CH:8]=[C:9]([CH2:11][O:12][C:13]4[CH:22]=[CH:21][C:20]5[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=5)[N:14]=4)[N:10]=[C:6]3[C:5]([N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)=[N:4][CH:3]=2)=[CH:34][CH:35]=1

Participants

3

Reactant 2

HCID 38450342-Chloropyridine-5-boronic acidHCID 117728336HCID 117728336, compound

Product 1

HCID 117728148HCID 117728148, compound

Procedure

Compound 49a was prepared from compound 15a and 2-chloro-5-pyridineboronic acid using the methods described in Example 1, Step G. Mass Spectrum (LCMS, ESI pos.) Calcd. For C25H21ClN6O2: 473.1 [M+H]. found 473.2

Sources & evidence

ORD record
ord-202a63445e394245b1f5966496aafeaf
Source dataset
uspto-grants-2016_02
Patent number
US09249163B2

Reaction notes

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