Trifluoroacetic acid → HCID 117728012, compound

Participants

Reaction Steps

Compound 49c was deprotected using TFA using the methods described in the Example 48, Step B to obtain the title compound. 1H-NMR (400 MHz, CDCl3) δ (ppm): 1.99-2.14 (m, 6H), 2.20-2.32 (m, 4H), 3.02-3.20 (m, 3H), 3.56-3.67 (m, 2H), 3.85-3.95 (m, 4H), 4.32-4.45 (m, 4H), 5.68 (s, 2H), 6.95 (d, J=8.8 Hz, 1H), 7.33-7.45 (m, 3H), 7.63 (td, J=7.7, 1.5 Hz, 1H), 7.69-7.75 (m, 1H), 7.76 (s, 1H), 7.83 (d, J=8.6 Hz, 1H), 7.89 (dd, J=8.1, 2.2 Hz, 1H), 8.00 (d, J=8.8 Hz, 1H), 8.70-8.79 (m, 1H), 9.34 (br. s., 1H), 9.79 (br. s., 1H). Mass Spectrum (LCMS, ESI pos.) Calcd. for C30H31N7O2: 522.2 [M+H]. found 522.2.

Provenance & Evidence