2-Cyanopyridine-5-boronic acid pinacol ester → HCID 117728040, compound

HRID 1772696Notes

Reaction equation

HRID 1772696 reaction equation
Br[C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][O:12][C:13]3[CH:22]=[CH:21][C:20]4[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=4)[N:14]=3)[N:10]=[C:6]2[C:5]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)=[N:4][CH:3]=1.[C:29]([C:31]1[CH:36]=[CH:35][C:34](B2OC(C)(C)C(C)(C)O2)=[CH:33][N:32]=1)#[N:30]>>[O:26]1[CH2:27][CH2:28][N:23]([C:5]2[C:6]3[N:7]([CH:8]=[C:9]([CH2:11][O:12][C:13]4[CH:22]=[CH:21][C:20]5[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=5)[N:14]=4)[N:10]=3)[C:2]([C:34]3[CH:35]=[CH:36][C:31]([C:29]#[N:30])=[N:32][CH:33]=3)=[CH:3][N:4]=2)[CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 164141882-Cyanopyridine-5-boronic acid pinacol esterHCID 117728336HCID 117728336, compound

Product 1

HCID 117728040HCID 117728040, compound

Procedure

Compound 54a was prepared from compound 31b and 2-cyanopyridine-5-boronic acid pinacol ester using the methods described in Example 1, Step G. Mass Spectrum (LCMS, ESI pos.) Calcd. for C26H21N7O2: 464.2 [M+H]. found 464.2.

Sources & evidence

ORD record
ord-4e6076f4224f4917976b6f3c1c5fbe93
Source dataset
uspto-grants-2016_02
Patent number
US09249163B2

Reaction notes

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