4-(5-Bromo-2-(2-(quinolin-2-yl)ethyl)imidazo[1,2-a]pyrazin-8-yl)morpholine → HCID 178419989, compound

Participants

Reaction Steps

The title compound 36 was prepared from compound 3a and compound 63c using the methods described in Example 1, Step G. Subsequently, the SEM group was removed using the methods described in Example 37, Step C. 1H-NMR (400 MHz CDCl3) δ (ppm): 3.22-3.32 (m, 2H), 3.35-3.43 (m, 2H), 3.83 (br. s., 4H), 4.14 (br. s., 4H), 7.17-7.30 (m, 3H), 7.31-7.39 (m, 4H), 7.48-7.59 (m, 1H), 7.73 (br. s., 1H), 7.76-7.88 (m, 2H), 8.01 (d, J=8.6 Hz, 1H), 8.10 (d, J=8.6 Hz, 1H). Mass Spectrum LCMS, ESI (pos.) Calcd. for C29H26N8OS: 535.0 [M+H]. found 535.6.

Provenance & Evidence