反应详情

温度

100 °C

Into a 250 mL sealed tube was placed compound 90d (50.0 g, 184 mmol) and NH4OH (150 mL). The resulting mixture was stirred overnight at 100° C. Upon cooling, a solid was collected by filtration and dried in an oven under reduced pressure to obtain the compound 90e as a grey solid (28.0 g, 66% yield), which was used in next step without further purification.

1. customInto a 250 mL sealed tube
2. temperatureUpon cooling
3. filtrationa solid was collected by filtration
4. customdried in an oven under reduced pressure