HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-(6-methoxy-5-methylpyridin-3-yl)-2-nitrobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | 6-Methoxy-5-methylpyridin-3-amine | HCID 40786903 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-(6-methoxy-5-methylpyridin-3-yl)-2-nitrobenzenesulfonamide | HCID 90022532 | 76.3% |
Reaction Steps
The title compound (2.69 g, 8.32 mmol) was prepared from 2-nitrobenzenesulfonyl chloride (2.41 g, 10.9 mmol), 6-methoxy-5-methylpyridin-3-amine (1.66 g, 12.0 mmol) and pyridine (2.64 mL, 32.7 mmol) in 1,4-dioxane (25 mL) at rt using the methods of (IntA1), step 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-85ad24ff990e4b03ad86d11d5a177d81 |
| Source note | uspto-grants-2016_02 |