3,4-Dimethylaniline → HCID 43388249, compound

HRID 1772905Notes

Reaction equation

HRID 1772905 reaction equation
[Cl:1][C:2]1[C:7]([S:8](Cl)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][C:19]=1[CH3:20])[NH2:16]>O1CCOCC1>[Cl:1][C:2]1[C:7]([S:8]([NH:16][C:15]2[CH:17]=[CH:18][C:19]([CH3:20])=[C:13]([CH3:12])[CH:14]=2)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 72483,4-DimethylanilineHCID 102199682-Chloropyridine-3-sulfonyl chloride

Product 1

HCID 43388249HCID 43388249, compoundYield 62.6%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound (966 mg, 3.26 mmol) was prepared from 2-chloropyridine-3-sulfonyl chloride (1.11 g, 5.21 mmol) and 3,4-dimethylaniline (698 mg, 5.73 mmol) in 1,4-dioxane (30 mL) using the methods of (IntC1).

Sources & evidence

ORD record
ord-7e824c02b678416dbd906d347fd90408
Source dataset
uspto-grants-2016_02
Patent number
US09249160B2

Reaction notes

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